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USC College > Faculty > Departments > Department of Biological Sciences > Oscar Aparicio
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Oscar Aparicio
Associate Professor of Biological Sciences

Contact Information
Office: RRI 219B
Phone: (213)821-1269
E-mail: oaparici@usc.edu

 

Education
B.S. Microbiology, University of Florida, 5/1987
Ph.D. Molecular Genetics & Cell Biology, University of Chicago, 12/1993
 

Postdoctoral Training
Postdoctoral Research Fellow, Massachusetts Institute of Technology, 11/01/1994-08/31/1999  
 

Academic Appointment, Affiliation, and Employment History

Tenure Track Appointments
Associate Professor, University of Southern California, 05/01/2005-  
Assistant Professor, University of Southern California, 09/01/1999-05/01/2005  
 

PostDoctoral Appointments
Postdoctoral Research Fellow, Massachusetts Institute of Technology, 11/01/1994-08/31/1999  
 

Other Employment
Congressional Science Fellow, American Society for Microbiology, 09/01/1993-08/31/1994  
 

Description of Research

Summary Statement of Research Interests
Professor Aparicio's research is focused on three related topics: (1) regulation of chromosomal DNA replication and the cell cycle in eukaryotic cells; (2) the role of cell cycle checkpoints in monitoring the integrity of chromosomal DNA replication and linking replication to cell cycle progression, DNA repair, and mitosis; (3) the influence of higher order chromatin structures/modifications (e.g.: heterochromatin) on the activity, timing, or replication origin activation during S phase. Aparicio employs a combination of molecular genetic, biochemical, physiological, and genomic methods in his studies. A full understanding of these mechanisms will provide important insights into the regulation of gene expression and organismal development under normal circumstances and the development of cancer when these processes go awry.
 

Research Keywords
DNA replication, DNA repair, chromatin, checkpoints, cell cycle, replication origins, replication forks, budding yeast, S. cerevisiae, genome
 

Research Specialties
Biochemistry, Molecular Biology, DNA replication, Genetics, S. cerevisiae
 

Affiliations with Research Centers, Labs, and Other Institutions
USC/Norris Comprehensive Cancer Center,http://ccnt.hsc.usc.edu/
 
 
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