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Biographical Sketch
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Peter Calabrese received his undergraduate degree in mathematics from the University of Maryland, College Park; his Ph.D. in applied mathematics from Cornell University (Rick Durrett thesis advisor); and was a National Science Foundation mathematics post-doctoral fellow at the University of Southern California (Simon Tavaré sponsoring scientist). His research is in the field of computational biology, and he has collaborated with several molecular biology laboratories at USC.
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Education
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 Ph.D. Applied Mathematics, Cornell University, 2001
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Postdoctoral Training
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NSF Math Post-doctoral Fellow, University of Southern California, 2001-2003
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Description of Research
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Summary Statement of Research Interests
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I am interested in applying probability to problems in biology. I have worked on mathematical modeling both in terms of population genetics and stem cell dynamics. I have developed innovative computational approaches for inference from these complicated models. Perhaps more than most other computational biologists, I like to closely collaborate with biologists in terms of designing and analyzing experiments. I have also been involved with analyzing large genomic datasets. At USC, I have collaborated with the laboratories of Norman Arnheim, Magnus Nordborg, Myron Goodman, and Darryl Shibata.
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Research Keywords
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Population genetics,
Paternal age effect,
Recombination,
Approximate Bayesian Computation
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Publications
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Journal Article
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Qin, J., Calabrese, P., Tiemann-Boege, I., Shinde, D. N., Yoon, S. R., Gelfand, D., Bauer, K., Arnheim, N.
(2007).
The molecular anatomy of spontaneous germline mutations in human testes. PLoS Biol.
Vol. 5, pp. e224.
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Arnheim, N., Calabrese, P., Tiemann-Boege, I.
(2007).
Mammalian Meiotic Recombination Hot Spots. Annual Review of Genetics.
Vol. 41
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Calabrese, P.
(2007).
A population genetics model with recombination hotspots that are heterogeneous across the population. Proc Natl Acad Sci U S A.
Vol. 104, pp. 4748-52.
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Toomajian, C., Hu, T. T., Aranzana, M. J., Lister, C., Tang, C., Zheng, H., Zhao, K., Calabrese, P., Dean, C., Nordborg, M.
(2006).
A nonparametric test reveals selection for rapid flowering in the Arabidopsis genome. PLoS Biol.
Vol. 4, pp. e137.
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Tiemann-Boege, I., Calabrese, P., Cochran, D. M., Sokol, R., Arnheim, N.
(2006).
High-resolution recombination patterns in a region of human chromosome 21 measured by sperm typing. PLoS Genet.
Vol. 2, pp. e70.
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Chelico, L., Pham, P., Calabrese, P., Goodman, M. F.
(2006).
APOBEC3G DNA deaminase acts processively 3' --> 5' on single-stranded DNA. Nat Struct Mol Biol.
Vol. 13, pp. 392-9.
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