 |
Lei Li
Associate Professor of Biological Sciences and Mathematics
Contact Information
Office: MCB 416E
Phone: (213)740-2407
E-mail:
lilei@usc.edu
LINKS
Personal Website
|
Education
|
 B.S. Mathematics, Peking University, 7/1988
|
|
M.S. Probability and Statistics, Peking University, 7/1991
|
|
Ph.D. Statistics, University of California, Berkeley, 5/1998
|
| |
Postdoctoral Training
|
|
Postdoc, UCLA,
Fall
2000
|
| |
Academic Appointment, Affiliation, and Employment History
|
|
Assistant Professor, Florida State University, 08/01/1998-05/30/2002
|
| |
Description of Research
|
Summary Statement of Research Interests
|
|
Professor Li’s research on computational biology and genomics centers around the mathematical and statistical modeling and software development of bio-measurement and biotechnology, genome biology. (1) Detection and understanding of expression differentiation of yeast life span; (2) Improvement of DNA sequencing accuracy and polymorphism detection; (3) Information-theoretic perspective of genomic data; (4) Statistical problems in optical mapping. His research on probability and statistics include (1) time series analysis and signal processing: (2) computation.
|
| |
Research Specialties
|
|
Statistical modeling and computation,
Signal processing,
DNA sequencing,
Microarray analysis,
Functional genomics
|
| |
Affiliations with Research Centers, Labs, and Other Institutions
|
|
Center for Computational and Experimental Genomics,http://www-hto.usc.edu
|
| |
Publications
|
Book Chapter
|
|
Li, L. M.
(2003).
Blind Inversion needs distribution (BIND): the general notion and case studies, in Festschrift for Professor Speed’s 60th Birthday. (Vol. 40). pp. 273-293. IMS Lecture Note Series.
|
| |
Journal Article
|
|
Cheng, C., Yan, X., Sun, F., Li, L. M.
(2007).
Inferring activity changes of transcription factors by binding association with sorted expression profiles. BMC Bioinformatics.
|
|
Cheng, C., Fabrizio, P., Ge, H., Wei, M., Longo, V. D., Li, L. M.
(2007).
Significant and Systematic Expression differentiation in Long-lived Yeast Strains. PLoS ONE.
Vol. 2 (10), pp. e1095.
|
|
Kim, J. H., Waterman, M. S., Li, L. M.
(2007).
Diploid Genome Reconstruction of Ciona intestinalis and Comparative Analysis with Ciona savignyi. Genome Research.
Vol. 17, pp. 1101-1110.
|
|
Cheng, C., Fabrizio, P., Ge, H., Longo, V., Li, L. M.
(2007).
Inference of Transcription Modificiation in Long-live Yeast Strains from their Expression Profiles. BMC Genomics.
Vol. 8, pp. 219-228.
|
|
Kitsantas, P., Hollander, M., Li, L. M.
(2007).
Assessing the Stability of Classifcation Trees. Journal of Statistical Planning and Inference.
Vol. 137, pp. 3917 – 3929.
|
|
Kim, J. H., Waterman, M. S., Li, L. M.
(2007).
Accuracy Assessment of Diploid Consensus Sequences. IEEE/ACM Transactions on Computational Biology and Bioinformatics.
Vol. 4, pp. 88-97.
|
|
Li, H., Valouev, A., Schwartz, D. C., Waterman, M. S., Li, L. M.
(2007).
A Quantile Method for Sizing Optical Maps. Journal of Computational Biology.
Vol. 14 (3), pp. 255–266.
|
|
Kitsantas, P., Hollander, M., Li, L. M.
(2006).
Using classification trees to assess low birth weight outcomes. Journal Artificial Intelligence in Medicine.
Vol. 38, pp. 275—289.
|
|
Cheng, C., Ma, X., Yan, X., sun, F., Li, L. M.
(2006).
MARD: A New Method to Detect Differential Gene Expression in Treatment-Control Time Courses. Bioinformatics.
Vol. 21, pp. 2650-2657.
|
|
Nicolas, P., Sun, F., Li, L. M.
(2006).
A model-based approach to selection of tag SNPs. BMC Bioinformatics.
Vol. 7, pp. 303.
|
|
Li, L. M.
(2006).
Some Notes on Mutual Information between Past and Future. Journal of Time Series Analysis.
Vol. 27, pp. 309–322.
|
|
Valouev, A., Li, L. M., Liu, Y., Schwartz, D. C., Yang, Y., Zhang, Y., Waterman, M. S.
(2006).
Alignment of Optical Maps. Journal of Computational Biology.
Vol. 13, pp. 442–462.
|
|
Cheng, C., Li, L. M.
(2005).
Sub-array Normalization Subject to Differentiation. Nucleic Acids Research.
Vol. 33(17), pp. 5565-5573.
|
|
Li, L. M.
(2005).
Factorization of moving-average spectral densities by state-space representations and stacking. Journal of Multivariate Analysis.
Vol. 96, pp. 425-438.
|
|
Li, L. M., Lu, H.
(2005).
Explore Biological Pathways from Noisy Array Data by Directed Acyclic Boolean Networks. Journal of Computational Biology.
Vol. 12, pp. 170-185.
|
|
Fabrizio, P., Li, L. M., Longo, V. D.
(2004).
Analysis of Gene Expression Profile in Yeast Aging Chronologically. Mechanisms of Ageing and Development.
Vol. 126, pp. 11-16.
|
|
Li, M. L., Nordborg, M., Li, L. M.
(2004).
Adjust quality scores from alignment and improve sequencing accuracy. Nucleic Acids Research.
Vol. 32, pp. 5183-5191.
|
|
Li, L. M.
(2004).
An Algorithm for computing exact least trimmed squares estimate of simple linear regression with constraints. Computational Statistics and Data Analysis.
Vol. 48, pp. 717-734.
|
|
Li, L. M., Kim, J. K., Waterman, M. S.
(2004).
Haplotype reconstruction from SNP alignment. Journal of Computational Biology.
Vol. 11, pp. 505-516.
|
|
Li, L. M., Speed, T. P.
(2004).
Deconvolution of sparse positive spikes. Journal of Computational and Graphical Statistics.
Vol. 13 (1-18)
|
|
Rosenberg, N. A., Li, L. M., Ward, R., Pritchard, J. K.
(2003).
Informativeness of genetic markers for inference of ancestry. Journal of American Human Genetics.
Vol. 73, pp. 1402-1422.
|
|
Li, L.
(2002).
DNA sequencing and parametric deconvolution. Statistica Sinica.
Vol. 12, pp. P179-202.
|
|
Li, L. M., Speed, T. P.
(2000).
Parametric Deconvolution of Positive Spike Trains. Annals of Statistics.
Vol. 28, pp. 1279-1301.
|
|
Li, L. M., Yu, B.
(2000).
Iterated-logarithmic Expansion of the Pathwise Code Lengths for Exponential Families. IEEE Transactions on Information Theory.
Vol. 46, pp. 2683-2689.
|
|
Li, L. M., Speed, T. P.
(2000).
Estimation of the Color Separation Matrix in Four-dye Fluorescence-based DNA Sequencing. Electrophoresis.
Vol. 20, pp. 1433-1442.
|
|
Kheterpa, I., Li, L. M., Speed, T. P., Mathies, R. A.
(1998).
A three-color labeling Approach for DNA sequencing using energy transfer primers and capillary electrophoresis. Electrophoresis.
Vol. 19, pp. 1403-1414.
|
|
Li, L. M., Xie, Z.
(1996).
Model selection and order determination for time series by information between the past and the future. Journal of Time Series Analysis.
Vol. 17, pp. 65-84.
|
|
Li, L. M.
(1994).
A method to factorize spectral densities of multiple moving average processes. Journal of Systems Sciences and Mathematics.
Vol. 7, pp. 169-176.
|
| |
| |
|
Faculty may update their profile by logging into the College portal from a computer on campus or off-campus via a VPN connection.
|
|
 |
|
