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Lorraine Turcotte
Associate Professor of Kinesiology and Biological Sciences
Contact Information
Office: PED 107 Phone: (213)740-8527
E-mail:
turcotte@usc.edu
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Education
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B.Ed. Physical Education, McGill University, Montreal, Canada, 6/1981
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M.S. Exercise Physiology, University of Massachusetts, Amherst, 5/1984
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Ph.D. Physiology, University of California, Berkeley, 5/1988
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Postdoctoral Training
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Post-Doctoral Fellow, Clinical Research Institute, Montreal, Canada, 08/01/1991-06/30/1993
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Post-Doctoral Fellow, August Krogh Institute, University of Copenhagen, 08/01/1988-07/01/1991
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Academic Appointment, Affiliation, and Employment History
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Chair, Department of Kinesiology, University of Southern California, 01/01/2004-
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Associate Professor, Department of Biological Sciences, University of Southern California, 01/01/2003-
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Associate Professor, University of Southern California, 01/01/1999-
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Co-Director, Metabolic Regulation Lab, University of Southern California, 01/01/1994-
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Assistant Professor, University of Southern California, 01/01/1993-01/01/1999
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Zumberge Fellow, University of Southern California, 01/01/1994-01/01/1996
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Post-Doctoral Fellow, Centre de Recherche/Hotel-Dieu Hospital, Canada, 01/01/1991-01/01/1993
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Post-Doctoral Fellow, University of Copenhagen, Denmark, 01/01/1988-01/01/1991
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Description of Research
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Summary Statement of Research Interests
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Research focus is on elucidating the cellular and hormonal signaling intermediates that regulate fatty acid metabolism by muscle and how these intermediates are affected by obesity, insulin resistance and exercise
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Affiliations with Research Centers, Labs, and Other Institutions
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Diabetes Research Center, Member
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Metabolic Regulation Lab, Co-Director
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Publications
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Abstract
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Kelly, K. R., Turcotte, L. P.
(2006).
Chronic activation of AMPK enhances insulin-sensitive fatty acid uptake but not oxidation in L6 cells. FASEB J.
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Raney, M. A., Turcotte, L. P.
(2006).
Cross-talk between CaMKII and AMPK is associated with increased FA metabolism in contracting rodent muscle. FASEB J.
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Book Chapter
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Turcotte, L. P.
(2006).
Lipid metabolism during exercise. pp. p.105-136. Champaign, Illinois: Exercise Metabolism/Human Kinetics.
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Journal Article
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Todd, M. K., Watt, M. J., Le, J., Hevener, A. L., Turcotte, L. P.
(2007).
Thiazolidinediones enhance skeletal muscle triacylglecerol synthesis while protecting against fatty acid-induced inflammation and insulin resistance. Am J Physio Endocrinol Metab.
Vol. 292, pp. E485-E493.
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Raney, M. A., Turcotte, L. P.
(2007).
Evidence for the regulation of contraction-induced fatty acid oxidation via extracellular signal-regulated kinase 1/2 activation independent of changes in fatty acid uptake. Metabolism.
Vol. 56, pp. 1192-1200.
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Berthiaume, M., Laplante, M., Festuccia, W., Cianflore, K., Turcotte, L., Joanisse, D., Olivecrone, G., Deshaies, Y.
(2007).
11-ß-HSD-1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids towards oxidative tissues. Am J Physiol Endocrinol Metab.
Vol. 293, pp. E1054-E1052.
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Raney, M. A., Turcotte, L. P.
(2006).
Regulation of contraction-induced FA uptake and oxidation by AMPK and ERK1/2 is intensity dependent in rodent muscle. Am J Physiol Endocrinol Metab.
Vol. 291, pp. E1220-E1227.
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Raney, M. A., Yee, A. J., Todd, M. K., Turcotte, L. P.
(2005).
AMPK activation is not critical in the regulation of muscle FA uptake and oxidation during low-intensity muscle contraction. Am J Physiol Endocrinol Metab.
Vol. 288, pp. E592-E598.
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Turcotte, L. P., Raney, M. A., Todd, M. K.
(2005).
ERK1/2 inhibition prevents contraction-induced increase in plasma membrane FAT/CD36 content and FA uptake in rodent muscle. Acta Physiol Scand.
Vol. 184, pp. 131-139.
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Tucker, M. Z., Turcotte, L. P.
(2005).
Brief food restriction in old animals decreases TG content and insulin-stimulated TG synthesis. J Gerontol Biol Sci.
Vol. 60A, pp. 157-164.
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Todd, M. K., Yaspelkis III, B. B., Turcotte, L. P.
(2005).
Short-term leptin treatment increases fatty acid uptake and oxidation in muscle of high fat-fed rats. Metabolism.
Vol. 54, pp. 1218-1224.
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Tucker, M. Z., Turcotte, L. P.
(2003).
Aging is associated with elevated muscle triglyceride content and increased insulin-stimulated fatty acid uptake. Am J Physiol Endocrinol Metab.
Vol. 283, pp. E827-E835.
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Turcotte, L. P.
(2003).
Mitochondria: Biogenesis, structure and function. Med Sci Sports & Exerc.
Vol. 35, pp. 82-85.
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Tucker, M. Z., Turcotte, L. P.
(2002).
Impaired fatty acid oxidation in muscle of aging rats perfused under basal conditions. Am J Physiol Endocrinol Metab.
Vol. 282, pp. E1102-E1109.
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Turcotte, L. P., Tucker, M. Z.
(2002).
Brief food restriction increases FA oxidation and glycogen synthesis under insulin-stimulated conditions. Am J Physiol Regulatory Integrative and Comp Physiol.
Vol. 282, pp. R1210-R1218.
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Yee, A. J., Turcotte, L. P.
(2002).
Insulin fails to alter plasma LCFA metabolism in muscle perfused at similar glucose uptake. Am J Physiol Endocrinol Metab.
Vol. 283, pp. E73-E77.
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Turcotte, L. P.
(2002).
High carbohydrate availabillity increases LCFA uptake and decreases LCFA oxidation in perfused muscle. Am J Physiol Endocrinol Metab.
Vol. 282, pp. E177-E183.
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Luiken, J. F., Arumugan, Y., Dyck, D. J., Bell, R. C., Pelsers, M. M., Turcotte, L. P., Tandon, N. N., Glatz, J. C., Bonen, A.
(2001).
Increased rates of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats. J Biol Chem.
Vol. 276, pp. 40567-40573.
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Turcotte, L. P., Swenberger, J. R., Tucker, M. Z., Yee, A. J.
(2001).
Increased fatty acid uptake and altered fatty acid metabolism in insulin-resistant muscle of obese Zucker rats. Diabetes.
Vol. 50, pp. 1389-1396.
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Turcotte, L. P., Swenberger, J. R., Tucker, M. Z., Yee, A. J., Trump, G., Luiken, J. F., Bonen, A.
(2000).
Muscle palmitate transport and binding are saturable and inhibited by antibodies to FABP (PM). Mol Cell Biochem.
Vol. 210, pp. 53-63.
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Gazdag, A. C., Wetter, T. J., Davidson, R. T., Robinson, K. A., Buse, M. G., Yee, A. J., Turcotte, L. P., Carter, G. D.
(2000).
Lower calorie intake enhances muscle insulin action and reduces hexosamine levels. Am J Physiol Regulatory Integrative & Comp Physiol.
Vol. 278, pp. R504-R512.
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Turcotte, L. P.
(1999).
Nutritional aspects of exercise. Role of fats in exercise: Types and quality. Clinics in Sports Medicine.
Vol. 18, pp. 485-498.
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Honors and Awards
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Fellow, American College of Sports Medicine, Fellow, 1996-
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Remarkable Women Award, University of Southern California, 2004
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Innovative Teaching Award: USC Center for Excellence in Teaching Innovative Undergraduate Teaching Award, 2002-2003
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Faculty of the Month, Mortar Board National Honor Society, 2001
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Undergraduate Teaching Award, 2001
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Innovative Teaching Award: USC Center for Excellence in Teaching Innovative Undergraduate Teaching Award, 2000-2001
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Professor of the Year, Gamma Sigma Alpha Honor Society, 1999
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Service to the Profession
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Editorships and Editorial Boards
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Associate Editor, Exercise and Sport Sciences Reviews, 2002-2005
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Editorial Board, Health and Fitness Journal, 2001-2004
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Professional Offices
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Executive Council, American College of Sports Medicine, Southwest Chapter, 07/01/2000-06/30/2003
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Professional Memberships
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American Physiological Society, Member, 1993-
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American Diabetes Association, Member Council on Exercise, 1988-
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American College of Sports Medicine, Fellow, 1982-
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International Society for the Study of Fatty Acids and Lipids, Member, 1995-2004
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