Publications

PUBLICATIONS FROM THE STUDY OF DEMENTIA IN SWEDISH TWINS

Reynolds, C.A., Hong, M.G., Eriksson, U.K., Blennow, K., Johansson, B., Malmberg, B., Berg, S., Gatz, M., Pedersen, N.L., Bennet A.M., & Prince, J.A. (2009). Sequence variation in SORL1 and dementia risk in Swedes. Neurogenetics. [Epub ahead of print]

Hassing, L.B., Dahl, A., Thorvaldsson, B., Berg, S., Gatz, M., Pedersen, N.L., & Johansson, B. (2009). Overweight in midlife and risk of dementia: A 40-year follow-up study. International Journal of Obesity, 33, 893-898.

Reynolds, C.A., Hong, M.G., Eriksson, U.K., Blennow, K., Bennet, A.M., Johansson, B., Malmberg, B., Berg, S., Wiklund, F., Gatz, M., Pedersen, N.L., & Prince, J.A. (2009). A survey of ABCA1 sequence variation confirms association with dementia. Human Mutation, 30, 1348-1354.

Brommelhoff, J.A., Gatz, M, Johansson, B., McArdle, J.J., Fratiglioni, L., & Pedersen, N.L. (2009). Depression as a risk factor or prodromal feature for dementia? Findings in a population-based sample of Swedish twins. Psychology and Aging, 24, 373-384.

Dahl, A., Hassing, L.B., Fransson, E., Berg, S., Gatz, M., Reynolds, C.A., & Pedersen, N.L. (2009). Being overweight in midlife is associated with lower cognitive ability and steeper cognitive decline in later life. Journals of Gerontology: Medical Sciences. [Epub ahead of print]

Xu, W., Qiu, C., Gatz, M., Pedersen, N.L., Johansson, B., & Fratiglioni, L. (2009). Mid-and late-life diabetes in relation to the risk of dementia: A population-based twin study. Diabetes, 58, 71-77.

Wirdefeldt, K., Gatz, M., Bakaysa, S.L., Fiske, A., Glensburg, M., Petzinger, G.M., Widner, H., Lew, M.F., Welsh, M., & Pedersen, N.L. (2008). Complete ascertainment of Parkinson disease in the Swedish Twin Registry. Neurobiology of Aging, 29, 1765-1773.

Hong, M., Reynolds, C., Gatz, M., Johansson, B., Palmer, J.C., Gu, H.F., et al. (2008). Evidence that the gene encoding insulin degrading enzyme influences human lifespan. Human Molecular Genetics, 17, 2370-2378.

Andel, R., Crowe, M., Pedersen, N.L., Fratiglioni, L., Johansson, B., & Gatz, M. (2008). Physical exercise at midlife and risk of dementia three decades later: A population-based study of Swedish twins. Journals of Gerontology: Medical Sciences, 63, M62-66.

Blom, E.S., Holmans, P., Arepalli, S., Adighibe, O., Hamshere, M.L., Gatz, M., Pedersen, N.L., Bergem, A.L., Owen, M.J., Hollingworth, P., Goate, A., Williams, J., & Lannfelt, L. (2008). Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13? American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 147B, 778-783.

Eriksson, U.K., Gatz, M., Dickman, P.W., Fratiglioni, L., Pedersen, N.L. (2008). Asthma, eczema, rhinitis and the risk for dementia. Dementia & Geriatric Cognitive Disorders, 25, 148-156.

Fiske, A., & Gatz, M. (2007). The Apartment Test: Validity of a memory measure. Aging, Neuropsychology and Cognition, 14, 441-461.

Crowe, M., Andel, R., Pedersen, N.L., & Gatz, M. (2007). Do work-related stress and reactivity to stress predict dementia more than 30 years later? Alzheimer Disease and Associated Disorders, 21, 205-209.

Gatz, M., Mortimer, J.A., Fratiglioni, L., Johansson, B., Berg, S., Andel, R., Crowe, M., Fiske, A., Reynolds, C.A. & Pedersen, N.L. (2007). Accounting for the relationship between low education and dementia: A twin study. Physiology & Behavior, 92, 232-237.

Gatz, M. (2007). Genetics, dementia and the elderly. Current Directions in Psychological Science, 16, 123-127.

Crowe, M., Andel, R., Pedersen, N.L., Fratiglioni, L., & Gatz, M. (2006). Personality and risk of cognitive impairment 25 years later. Psychology and Aging, 21, 573-580.  abstract

Gatz, M., Prescott, C.A., & Pedersen, N.L. (2006). Lifestyle risk and delaying factors. Alzheimer Disease and Associated Disorders, 20, S84-S88. abstract

Gatz, M., Mortimer, J.A., Fratiglioni, L., Johansson, B., Berg, S., Reynolds, C.A. & Pedersen, N.L. (2006). Potentially modifiable risk factors for dementia in identical twins. Alzheimer's and Dementia, 2, 110-117. abstract

Gatz, M., & Pedersen, N.L. (2006). Commentary on "The NIH cognitive and emotional health project: Report of the critical evaluation study committee." What can be concluded? Alzheimer's & Dementia, 2, 91-92.

Reynolds, C.A., Fiske, A., Fratiglioni, L., Pedersen, N.L., & Gatz, M. (2006). Heritability of an age-dependent categorical phenotype: Cognitive dysfunction. Twin Research and Human Genetics, 9, 17-23. abstract

Reynolds, C.A., Prince, J.A., Feuk, L., Gatz, M., Brookes, A.J., & Pedersen, N.L. (2006). Longitudinal memory performance during normal aging: twin association models of APOE and other Alzheimer candidate genes. Behavior Genetics, 36, 1-10. abstract

Gatz. M., Reynolds, C.A, Fratiglioni, L., Johansson, B., Mortimer, J.A., Berg, S., Fiske, A., & Pedersen, N.L. (2006). Role of genes and environments for explaining Alzheimer’s disease. Archives of General Psychiatry, 63, 168-174. article

Read, S., Pedersen, N.L., Gatz, M., Berg, S., Vuoksimaa, E., Malmberg, B., Johansson, B., & McClearn, G.E. (2006). Sex differences after all those years? Heritability of cognitive abilities in old age. Journal of Gerontology: Psychological Sciences, 61B, P137-P143.

Reynolds, C.A., Jansson, M., Gatz, M., & Pedersen, N.L. (2006). Longitudinal change in memory performance associated with HTR2A polymorphism. Neurobiology of Aging, 27, 150-154. abstract

Gatz, M., Fiske, A., Reynolds, C.A., Johansson, B., Fratiglioni, L., & Pedersen, N.L. (2005). Performance on neurocognitive tests by co-twins to dementia cases compared to normal control twins. Journal of Geriatric Psychiatry and Neurology, 18, 202-207. abstract

Andel, R., Crowe, M., Pedersen, N.L., Mortimer, J., Crimmins, E., Johansson, B., & Gatz, M. (2005). Complexity of work and risk of Alzheimer's disease: A population-based study of Swedish twins. Journals of Gerontology: Psychology Sciences, 60, 251-258. abstract

Fiske, A., Gatz, M., Aadnoy, B., & Pedersen, N.L. (2005). Assessing age of dementia onset: Validity of informant reports. Alzheimer Disease and Associated Disorders, 19, 128-134. abstract

Rasgon, N.L., Magnusson, C., Johansson, A.L.V., Pedersen, N.L., Elman, S., & Gatz, M. (2005). Endogenous and exogenous hormone exposure and risk of cognitive impairment in Swedish twins: A preliminary study. Psychoneuroendocrinology, 30, 558-561. abstract

Heflin, L.H., Meyerowitz, B.E., Hall, P., Lichtenstein, P., Johansson, B., Pedersen, N.L., & Gatz, M. (2005). Cancer as a risk factor for long-term cognitive deficits and dementia. Journal of the National Cancer Institute, 97, 854-856. abstract

Reynolds, C.A., Turner, A., Gatz, M., & Pedersen, N.L. (2005). Comparative rating measures of health and environmental exposures: how well do twins agree. Twin Research and Human Genetics, 8, 113-119. abstract

Gatz, M. (2005). Educating the brain to avoid dementia: Can mental exercise prevent Alzheimer disease? PLoS Medicine, 2, 38-40. article

Wirdefeldt, K., Gatz, M., Pawitan, Y., & Pedersen, N.L. (2005). Risk and protective factors for Parkinson's disease: A study in Swedish twins. Annuals of Neurology, 57, 27-33. article

Reynolds, C.A., Finkel, D., McArdle, J.J., Gatz, M., Berg, S., & Pedersen, N.L. (2005). Quantitative genetic analysis of latent growth curve models of cognitive abilities in adulthood. Developmental Psychology, 41, 3-16. abstract

Gatz, M., Fratiglioni, L., Johansson, B., Berg, S., Mortimer, J.A., Reynolds, C.A., Fiske, A., & Pedersen, N.L. (2005). Complete ascertainment of dementia in the Swedish Twin Registry: the HARMONY study.  Neurobiology of Aging, 26, 439-447.

Katzov, H., Bennet, A., Kehoe, P., Wiman, B., Gatz, M., Blennow, K., Lenhard, B., Pedersen, N.L., deFaire, U., & Prince, J.A. (2004).  A cladistic model of ACE sequence variation with implications for myocardial infarction, Alzheimer’s disease, and obesity.  Human Molecular Genetics, 13 (21).

Blomqvist, M., Silburn, P.A., Buchanan, D.D., Andreasen, N., Blennow, K., Pedersen, N.L., Brookes, A.J., Mellick, G.D., & Prince, J.A. (2004). Sequence variation in the proximity of IDE may impact age at onset of both Parkinson's disease and Alzheimer's disease. Neurogenetics, 5, 115-119.

Jin, Y-P., Gatz, M., Johansson, B., & Pedersen, N.L. (2004). Sensitivity and specificity of dementia coding in two Swedish disease registries. Neurology, 63, 739-741.

Pedersen, N.L., Gatz, M., Berg, S., & Johansson, B. (2004).  How heritable is Alzheimer's disease late in life? Findings from Swedish Twins.  Annuals of Neurology, 55, 180-185. article

Kehoe, P.G., Katzov, H., Andreasen, N., Gatz, M., Wilcock, G.K., Cairns, N.J., Palmgren, J., deFaire, U., Brookes, A.J., Pedersen, N.L., Blennow, K., & Prince, J.A. (2004).  Common variants of ACE contribute to variable age-at-onset of Alzheimer’s disease.  Human Genetics, 114, 478-483.

Katzov, H., Chalmers, K., Palmgren, J., Andreasen, N., Johansson, B., Cairns, N.J., Gatz, M., Wilcock, G.K., Love, S., Pedersen, N.L., Brookes, A.J., Blennow, K., Kehoe, P.G., & Prince, J.A. (2004).  Genetic variants of ABCA1 modify Alzheimer disease risk and quantitative traits related to beta-amyloid metabolism.  Human Mutation, 23, 358-367.

Johansson, A, Katzov, H., Zetterberg, H., Feuk, L., Johansson, B., Bogdanovic, N., Andreasen, N., Lenhard, B., Brookes, A.J., Pedersen, N.L., Blennow, K., & Prince J.A. (2004). Variants of CYP46A1 may interact with age and APOE to influence CSF Abeta42 levels in Alzheimer's disease. Human Genetics, 114, 581-587.

Prince, J.A., Feuk, L., Gu, H.F., Johansson, B., Gatz, M., Blennow, K., & Brookes, A.J. (2003).  Genetic variation in a haplotype block spanning IDE influences Alzheimer disease.  Human Mutation, 22, 363-371.

Finkel, D., Reynolds, C.A., McArdle, J.J., Gatz, M., & Pedersen, N.L. (2003). Latent growth curve analyses of accelerating decline in cognitive abilities in adulthood. Developmental Psychology, 39, 535-550. abstract

Crowe, M., Andel, R., Pedersen, N.L., Johansson, B., & Gatz, M. (2003). Does participation in leisure activities lead to reduced risk of Alzheimer's disease? A Prospective study of Swedish twins. Journals of Gerontology: Psychological Sciences, 58B, P249-P255.

Gatz, M., Fiske, A., Reynolds, C.A., Wetherell, J.L., Johansson, B., & Pedersen, N.L. (2003). Sex differences in genetic risk for dementia. Behavior Genetics, 33, 95-105.

Ripatti, S., Gatz, M., Pedersen, N.L., & Palmgren, J. (2003).  A three-state frailty model for age at onset of dementia and death in Swedish twins. Genetic Epidemiology, 24, 139-149. 

Hassing, L.B., Johansson, B., Nilsson, S.E., Berg, S., Pedersen, N.L., Gatz, M., & McClearn, G. (2002).  Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: A population-based study of the oldest-old. International Psychogeriatrics, 14, 239-248.

Gatz, M., Reynolds, C.A., John, R., Johansson, B., Mortimer, J.A., & Pedersen, N.L. (2002). Telephone screening to identify potential dementia cases in a population-based sample of older adults. International Psychogeriatrics, 14, 273-289.

Reynolds, C.A., Finkel, D. Gatz, M., & Pedersen, N.L. (2002). Sources of influences on rate of cognitive change over time in Swedish twins: An application of latent growth models. Experimental Aging Research, 28, 407-433.

Watari, K., & Gatz, M. (2002). Dementia: Cross-cultural perspective on risk factors. Generations, 26, 32-38.

Wetherell, J.L., Reynolds, C.A. , Gatz, M., & Pedersen, N.L. (2002). Anxiety, cognitive performance and cognitive decline in normal aging. Journals of Gerontology: Psychological Sciences, 57B, P246-P255.

Reynolds, C.A., Gatz, M., & Pedersen, N.L. (2002). Individual variation for cognitive decline: Quantitative methods for describing patterns of change. Psychology and Aging, 17, 271-287.

Pedersen, N.L., Posner, S.F., & Gatz, M.  (2001). Multiple threshold models for genetic influences on age of onset for Alzheimer’s disease: Findings in Swedish twins. American Journal of Medical Genetics, 105, 724-728.

Andel, R., Gatz, M., Pedersen, N.L., Reynolds, C.A., Johansson, B., & Berg, S. (2001). Deficits in controlled processing may predict dementia: A twin study. Journals of Gerontology: Psychological Sciences, 56, P347-P355.

Gatz, M. Svedberg, P., Pedersen N.L., Mortimer, J.A., Berg, S., & Johansson, B. (2001). Education and the risk of Alzheimer's disease: Findings from the Study of Dementia in Swedish Twins. Journals of Gerontology: Psychological Sciences, P292-P300. 

Gatz, M., Pedersen, N.L., Crowe, M., & Fiske, A. (2000). Defining discordance in twin studies of risk and protective factors for late life disorders.  Twin Research, 3, 159-164.

Rowe, J.W. & Gatz, M. (2000). Implications of genetic knowledge for public policy. Generations, 24 (1), 79-83.

Reynolds, C.A., Wetherell, J.L., & Gatz, M. (1999). Heritability of Alzheimer's disease.  In B.Vellas & L.J. Fitten (Eds.), Research and practice in Alzheimer's disease and other dementias (Vol. 2) (pp. 175-191) New York: Springer Publishing.

Posner, S.F., Pedersen, N.L., & Gatz, M. (1999). The application of life table analysis to the onset of dementia in a genetically informative design. Neuropsychiatric Genetics, 88, 207-210.

Pedersen, N.L., Miller, B.L., Wetherell, J.L., Vallo, J., Toga, A.W., Knutson, N., Mehringer, C.M., Small, G.W., & Gatz, M. (1999).  Neuroimaging findings in twins discordant for Alzheimer's disease.  Dementia and Geriatric Cognitive Disorders, 10, 51-58.

Wetherell, J.L., Gatz, M., Johansson, B., & Pedersen, N.L. (1999).  History of depression and other psychiatric illness as risk factors for Alzheimer's disease in a twin sample.  Alzheimer Disease and Associated Disorders, 13, 47-52.

Pedersen, N.L., Berg, S., Johansson, B., Johansson, K., Viitanen, M., Winblad, B., & Gatz, M. (1998).  Genetiska Faktorer ligger ofta bakom Alzheimer's sjukdom: Stor tvillingstudie skall klarlagga sambanden arv-miljo.  Lakartindningen, 95, 2585-2588.

Feychting, M., Pedersen, N.L., Svedberg, P., Floderus, B., & Gatz, M. (1998).  Dementia and occupation exposure to magnetic fields.  Scandinavian Journal of Work, Environment & Health, 24, 46-53.

Gatz, M., Pedersen, N. L., Berg, S., Johansson, B., Johannson, K., Mortimer, J. A., Posner, S. F., Viitanen, M., Winblad, B., & Ahlbom, A. (1997). Heritability for Alzheimer's Disease: The study of dementia in Swedish twins. Journal of Gerontology: Medical Sciences, 52A, M117-125.

Gatz, M. & Pedersen, N.L. (1996).  Use of twin samples to estimate the heritability of Alzheimer's disease:  A methodological note.  Alzheimer's Research, 2, 229-231.

Pedersen, N. L., Reynolds, C. A., & Gatz, M. (1996). Sources of Covariation among Mini-Mental State Examination Scores, Education and Cognitive Abilities. Journal of Gerontology: Psychological Sciences, 51B, P55-P63.

Pedersen, N. L. (1996). Gerontological behavior genetics. In J. E. Birren & K. W. Schaie (Eds.), Handbook of the psychology of aging, Fourth edition. (pp. 59-77). San Diego: Academic Press.

Pedersen, N. L., Posner, S. F., & Gatz, M. (1995). Twin studies as tools for bridging the gap between genetics and epidemiology of dementia. In M. Bergener & S. I. Finkel (Eds.), Treating Alzheimer's and other dementias: Clinical application of recent research advances. (pp.527-544). New York: Springer Publishing Co.

Lannfelt, L., Pedersen, N. L., Lilius, L., Axelman, K., Johansson, K., Viitanen, M., & Gatz, M. (1995). Apolipoprotein ,4 allele in Swedish twins and siblings with Alzheimer's disease. Alzheimer Disease & Associated Disorders, 9, 166-169.

Johansson, B., Gatz, M., Berg, S., & Pedersen, N. (1995). Heterogeneity of impairment in dementia: Data from the Study of Dementia in Swedish Twins. In M. Bergener, Brocklehurst, J. C., & Finkel, S. I. (Ed.), Aging, health, and healing. (pp. 74-79). New York: Springer Publishing Co.

Gatz, M., Reynolds, C., Nikolic, J., Lowe, B., Karel, M., & Pedersen, N. (1995). An empirical test of telephone screening to identify potential dementia cases. International Psychogeriatrics, 7, 429-437.

Gatz, M. (1995). Questions that aging puts to preventionists. In L. Bond, S. Cutler & A. Grams (Eds.), Promoting successful and productive aging (pp. 36-50). Newbury Park: Sage.

Gatz, M., Lowe, B., Berg, S., Mortimer, J., & Pedersen, N. (1994). Dementia: Not just a search for the gene. The Gerontologist, 34, 251-255.

Breitner, J. C. S., Gatz, M., Bergem, A. L. M., Christian, J.C., Mortimer, J. A., McClearn, G. E., Heston, L. L., Welsh, K. A., Anthony, J. C., Folstein, M. F., & Radebaugh, T. S. (1993). Use of twin cohorts for research in Alzheimer's disease. Neurology, 43, 261-267.

Pedersen, N. L., Gatz, M., Winblad, B., Pearson, C. G., & Berg, S. (1989). Dementias in Swedish twins. In K. Iqbal, H. M. Wisniewski, & B. Winblad (Eds.), Alzheimer's disease and related disorders (Vol. 317, pp. 217 222). New York: Alan R. Liss.